Field Trials of Adjuvant and Saline Influenza Vaccines.
نویسندگان
چکیده
Satisfactory protection against influenza can be obtained by the use of vaccines which contain prevalent strains of killed influenza virus (e.g. Hawkins, Hatch, and McDonald, 1956; Meiklejohn, 1962). The antigenic material is usually suspended either in saline or in a vehicle which has an adjuvant effect. Unfortunately the antibody response after saline vaccine is relatively transient, even when a booster dose is given some weeks after the primary injection (Hennessy and Davenport, 1961). Saline vaccines also tend to produce unpleasant local and general reactions (MRC, 1957; Meichen, Rogan, and Howell, 1962). In contrast, enhanced and prolonged antibody
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ورودعنوان ژورنال:
- British journal of preventive & social medicine
دوره 19 شماره
صفحات -
تاریخ انتشار 1965